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CCRNHigh-YieldRespiratory 12%
modes, settings, alarms, and weaning parameters

Mechanical Ventilation

<105

RSBI

Rapid Shallow Breathing Index for weaning

≤-20

NIF

cmH2O minimum for extubation

30-45°

HOB Elevation

Ventilator bundle standard

Ventilator Modes

know the key difference between each mode

AC/VC

Assist-Control Volume

Delivers set tidal volume with every breath (patient or machine triggered). Most common initial mode.

AC/PC

Assist-Control Pressure

Delivers set pressure with every breath. Tidal volume varies. Useful when plateau pressures are high.

SIMV

Synchronized Intermittent

Set number of mandatory breaths, patient can take spontaneous breaths between. Used for weaning.

PSV

Pressure Support

Patient triggers every breath, machine provides pressure boost. Used for weaning and SBT.

APRV

Airway Pressure Release

Keeps lungs inflated at high pressure with brief releases. Used in severe ARDS for recruitment.

Ventilator Alarms

High Pressure (Obstruction)

  • Secretions in airway
  • Patient biting ETT
  • Bronchospasm
  • Pneumothorax
  • Patient-ventilator dyssynchrony

Low Pressure (Leak/Disconnect)

  • Circuit disconnection
  • ETT cuff leak
  • Loose connections
  • Chest tube air leak

Weaning and Extubation

RSBI = RR divided by TV. Under 105 predicts successful extubation. Over 105 predicts failure. Calculate it during a spontaneous breathing trial on minimal support.

Spontaneous breathing trial (SBT) on PSV 5-8 or T-piece for 30-120 minutes

RSBI <105 (respiratory rate / tidal volume in liters)

NIF ≤ -20 cmH₂O (adequate inspiratory strength)

PaO2/FiO2 >150-200 on FiO2 ≤40% and PEEP ≤5-8

Hemodynamically stable without high-dose vasopressors

Intact cough, gag reflex, and ability to manage secretions

Key Values to Memorize

RSBI <105 = success

NIF ≤-20 cmH₂O

HOB 30-45° always

Cuff pressure 20-30 cmH₂O

SBT 30-120 min

VAE bundle = HOB + oral care + DVT ppx + sedation vacation

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Exam Traps

High pressure alarm means check the PATIENT first

Secretions, biting the tube, bronchospasm, pneumothorax, and patient-ventilator dyssynchrony all cause high pressure alarms. Always assess the patient before troubleshooting the circuit. The exam will present a high alarm scenario and expect you to assess the patient, not disconnect tubing.

Auto-PEEP requires end-expiratory hold to detect

Auto-PEEP (intrinsic PEEP) occurs when air gets trapped. It is invisible on the ventilator display unless you perform an end-expiratory hold maneuver. Common in COPD and asthma. Treatment is reducing rate and increasing expiratory time.

RSBI under 105 predicts successful extubation

RSBI = respiratory rate divided by tidal volume (in liters). Under 105 suggests the patient can sustain spontaneous breathing. Over 105 predicts weaning failure. The exam expects you to calculate and interpret this.

Never extubate without meeting all weaning criteria

Adequate oxygenation, hemodynamic stability, ability to protect airway, minimal secretions, intact cough and gag, and passing a spontaneous breathing trial are all required. Skipping criteria leads to reintubation.

Alarm Priority

High pressure alarm? Check the PATIENT first (secretions, biting, bronchospasm). Then check the circuit. Patient always comes first.

Auto-PEEP in COPD

Auto-PEEP = air trapping. Common in COPD/asthma. Reduce rate, increase expiratory time. Perform end-expiratory hold to detect it.

1
The Ventilator

Think of the ventilator as a machine inflating a balloon (the lungs) over and over. Different modes control whether the machine decides the volume of air, the pressure of air, or lets the patient help.

2
High vs Low Alarms

High pressure alarm = something is making it harder to inflate the balloon (mucus plug, patient coughing, kinked tube). Low pressure alarm = air is escaping somewhere (disconnection, cuff leak). High = obstruction. Low = leak.

3
Auto-PEEP

Imagine not fully deflating the balloon before pumping more air in. Each breath traps a little more air. The balloon gets stretched tighter and tighter. That is auto-PEEP, and it is dangerous in patients who cannot exhale fully.

4
Weaning

Weaning is slowly letting the patient inflate their own balloon. RSBI measures whether they can do it without getting exhausted. Under 105 means they are strong enough. Over 105 means they are struggling.

High alarm = patient. Low alarm = circuit. RSBI under 105 = green light.
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Reviewed by Maya P., PrepSolution Content Editor, Critical Care Nursing
Sources verified against AACN 2026 standards
Updated May 2026